Beyond these direct antioxidant actions, HTY has reported to influence cellular redox homeostasis by modulating signaling pathways associated with antioxidant defense, most notably those linked nuclear factor erythroid 2related factor 2 (Nrf2), resulting in increased expression of phase II detoxification enzymes such as heme oxygenase-1 (HO-1), superoxide dismutase (SOD), catalase (CAT), and NAD(P)H quinone dehydrogenase 1 (NQO1) [6]
Biological characteristics of oocyte senescence Decline in fertility is due mainly to ovarian ageing, which is characterised by changes in the quantity and quality of oocytes
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This study evaluated the therapeutic potential of non-gene-edited human chemically induced pluripotent stem cell-derived neural stem cells (hCiPSC-NSCs) in a prenatal valproic acid (VPA)-induced rat model of ASD, using a dual-pathway administration strategy (intravenous systemic delivery combined with an intracerebroventricular boost)
